Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ TOPK/PBK Inhibitor, HI-TOPK-032
A cell-permeable, selective, ATP competitive, reversible inhibitor of T-LAK-cell-originated protein kinase (IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ CMP-Sialic Acid, Disodium Salt InSolution™
A 25 mM (10 mg/608 μL) sterile-filtered solution of CMP-Sialic Acid, Disodium Salt in H2O.
MilliporeSigma™ Calbiochem™ W-13, Hydrochloride
A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 58 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 68 μM).
MilliporeSigma™ Calbiochem™ Oxymetazoline Hydrochloride
Oxymetazoline Hydrochloride is an α2-Adrenergic receptor agonist. Enhances EGF- and PDGF-induced DNA synthesis.
MilliporeSigma™ Calbiochem™ PKM2 Activator IV, TEPP-46
A cell-permeable, potent, allosteric activator of PKM2 (AC50 = 92 nM).
MilliporeSigma™ Calbiochem™ Diclofenac Sodium
A cell-permeable, non-selective cyclooxygenase inhibitor (IC50 = 60 nM and 200 nM for ovine COX-1 and COX-2 respectively) and potent non-steroidal anti-inflammatory drug with analgesic activity.
MilliporeSigma™ Calbiochem™ FGF Receptor Tyrosine Kinase Inhibitor
The FGF Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 192705-79-6, controls the biological activity of FGF Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor VI, HNHA
The Histone Deacetylase Inhibitor VI, HNHA, also referenced under CAS 926908-04-5, controls the biological activity of Histone Deacetylase.
MilliporeSigma™ Calbiochem™ LSD1 Inhibitor VII, SP-2509
A cell-permeable, potent, selective, reversible inhibitor of Lysine-Specific Demethylase 1 (LSD1; IC50 = 13 nM; Ki = 31 nM).
MilliporeSigma™ Calbiochem™ 2-Guanidinoethylmercaptosuccinic Acid
Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM).
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor III, iCRT3
The β-Catenin/Tcf Inhibitor III, iCRT3 controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Bcl-2 Binding Peptide, Cell-Permeable, Negative Control
A cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.
MilliporeSigma™ Calbiochem™ Caspase-8 Inhibitor I, Cell-Permeable
The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Glucokinase Activator III, Ro-28-1675
A cell-permeable activator of glucokinase. Exhibits in vivo glucose-lowering and insulin-releasing activity
MilliporeSigma™ Calbiochem™ NMDAR2C/2D Inhibitor, DQP-1105
The NMDAR2C/2D Inhibitor, DQP-1105 controls the biological activity of NMDAR2C/2D. This small molecule/inhibitor is primarily used for Neuroscience applications.